Keep all medications away from children and pets. Once inside your body, ferric carboxymaltose releases iron into your system. Consult your pharmacist or local waste disposal company. This medicine may cause serious types . Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Joint pain. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Heart failure: Could a low sodium diet sometimes do more harm than good? Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. You should not receive Venofer if you have known allergies to iron sucrose. If you notice any changes to your normal blood pressure, call your doctor right away. This hormone is made by your kidneys. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. So we cant say for sure whether the drug is safe to use while youre pregnant. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Tell all of your health care providers that you take Venofer. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Injectafer is approved to treat iron deficiency anemia (IDA). In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Below are examples of these side effects. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Many patients with kidney disease cannot get enough iron from food and require injections. Pain, swelling, or redness at the injection site may occur. How is Venofer (iron sucrose) given? This treatment course is split into two doses of the drug, which are given at least 7 days apart. I actually was constipated after my 3rd but didn't think anything of it. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. But for other people, their anemia may come back after Injectafer treatment. Together, they can recommend ways to help you manage a body weight thats healthy for you. Venofer is given as an infusion into a vein. (A medication class describes a group of drugs that work in the same way.). . Brand-name medications usually cost more than generics. Things to remember when you fill your prescription. Check with your pharmacist. People from different ethnic backgrounds process medications differently. Throw away unused or expired drugs. Injectafer can cause mild or serious side effects. Low iron saturation, or iron deficiency, has various possible causes. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. They can tell you about other medications that may work well for you. One of the most commonly used tests to monitor IDA is the hemoglobin test. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. The infusion will take between 15-30 minutes if it is given in. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Before taking Injectafer, talk with your doctor about your health history. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Orofer S 50 Injection 1 Injection in 1 Packet 147. FG Trade/E+ sia Getty Images While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. A lack of iron can lead to iron deficiency anaemia if left untreated. Vomiting. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. MNT is the registered trade mark of Healthline Media. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. In the second group, some people switched from taking iron by mouth to taking Injectafer. weakness. These nutrients include iron, vitamin B12, and folate. In one study, people were given either Injectafer or an iron replacement drug called Venofer. Have blood work checked as you have been told by the doctor. Its not known how common delayed allergic reaction might be in other people using Injectafer. HRT, like other medications, does have some side effects and these are thought to be quite common. Do not start, stop, or change the dose of any drug without checking with your doctor. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Mild side effects of Injectafer can include:*. How long does iron infusion stay in your system? What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. What Is the Cost of Whole Genome Sequencing (WGS)? If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. * Feraheme has a boxed warning for this side effect. So you wont pick up this medication from a pharmacy. But for other people, doing so could lead to having too much iron in their body. 4 0 obj Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. WebMD does not provide medical advice, diagnosis or treatment. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Your doctor will determine the best dosage to fit your needs. Answer by DrLact: About Venofer usage in lactation. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). If youre interested in finding an alternative to Injectafer, talk with your doctor. Possibleside effectsareweight gainand suicidal thoughts. dizziness. Otherwise, call a poison control center right away. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. This product may contain inactive ingredients, which can cause allergic reactions or other problems. muscle pain. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Which tests can diagnose iron deficiency anemia? (For more information on Venofer, see the Injectafer vs. Venofer section above). With IDA, you have low hemoglobin levels. After the infusion, you can drive yourself home and return to your usual activities. There isnt a known interaction between Injectafer and alcohol. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Some people only need one treatment course of Injectafer. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. And these two doses need to be separated by at least 7 days. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Drug class: Iron products. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Its possible to get rid of or reduce the severity ofside effects. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Someside effectsare temporary or last as long as the person continues takingprescription medicine. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. They can recommend if this is safe for you to do. (A medication class is a group of medications that work in a similar way.). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Theseside effectsmay last as long as they are undercancer treatment. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. During pregnancy, this medication should be used only when clearly needed. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.